Clarifying differentiator, iCON™ Staining System

iCON™ Clarifying Differentiator is designed to be used after hematoxylin staining to increase transparency and definition of hematoxylin and eosin staining. Clarifying differentiator has the additional benefits of removing nonspecific hematoxylin and slide adhesive staining. When slides are over stained, the differentiator may be used to remove unwanted hematoxylin staining of ground substance and mucin, which results in delineated crisp blue-purple nuclear chromatin staining and an exceptional cytoplasmic transparency and definition.

An increase of exposure to our clarifying differentiator results in greater cytoplasmic differentiation of muscle fibers and collagen. The recommended exposure time to the differentiator is thirty seconds to one minute. There should be no noticeable decrease in hematoxylin staining of nuclear chromatin.

Acid alcohol differentiators can result in inconsistent differentiation of ground substance staining, blue mucin staining, slide adhesive staining, and murky cytoplasmic staining. Undifferentiated nuclear staining is seen on occasion as well as pale nuclear staining. This is due to the aggressiveness of acid alcohol differentiators.

iCON™ Clarifying Differentiator can be used with any staining protocol to improve staining results. It may be used on all automatic stainers as well as in manual staining. The shelf life of ICON™ Clarifying Differentiator is two years versus the standard one year for competitive products.

Features:
- Increases transparency and definition of hematoxylin and eosin staining
- Recommended exposure time to the differentiator is thirty seconds to one minute
- Can be used with any staining protocol to improve staining results
- May be used on all automatic stainers as well as in manual staining
- Two year shelf life

Packaging options:
ES36551-4G: 4 x 1 Gallon
ES36551-1-GAL: 1 Gallon

Product Documents:
Product Literature
Product Brochure
Product SDS