CD5
Details
CD5 is a glycoprotein monomer with a molecular weight of 67 kDa and belongs to the scavenger receptor cysteine-rich (SRCR) family, which consists of extracellular domain-like structures. It possesses a large cytoplasmic domain that is suitable for signal transduction.
The CD5 antibody is commonly used as a T-cell marker, as it reacts with T-lymphocyte subsets. However, it is also known to react with a range of neoplastic B-cells, including B-cell Chronic Lymphocytic Leukemia (B-CLL), B-cell Small Lymphocytic Lymphoma (BSLL), and Mantle Cell Lymphoma. CD5 antibody expression is found in these B-cell malignancies and can aid in their identification and classification.
Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product.
| Specifications: | |
|---|---|
| Intended Use: | This antibody is intended for use in Immunohistochemical applications on formalin-fixed paraffin-embedded tissues (FFPE). The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist. |
| Format: | Prediluted, Concentrated |
| Antibody type: | Mouse Monoclonal |
| Isotype: | IgG |
| Localization: | Membranous |
| Clone: | C6A10 |
| Reactivity: | Human Paraffin |
| Preparation: | This antibody is derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide. |
Prediluted:
1mL: ES35803-P-1ML
3mL: ES35803-P-3ML
6mL: ES35803-P-6ML
Concentrated:
0.1mL: ES35803-C-01ML
0.5mL: ES35803-C-05ML
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